Article
LGI Proteins and Epilepsy in Human and Animals.
Journal of veterinary internal medicine - 1 Jan 2000
Pakozdy A, Patzl M, Zimmermann L, Jokinen T S, Glantschnigg U, Kelemen A, Hasegawa D
Abstract excerpt
Leucine-rich glioma-inactivated (LGI) protein was first thought to have a suppressor effect in the formation of some cancers. Developments in physiology and medicine made it possible to characterize the function of the LGI protein family and its crucial role in different conditions more precisely. These proteins play an important role in synaptic transmission, and dysfunction may cause hyperexcitability. Genetic...
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