Article
The LGI1/epitempin gene encodes two protein isoforms differentially expressed in human brain.
Journal of neurochemistry - 1 Aug 2006
Furlan Sandra, Roncaroli Federico, Forner Francesca, Vitiello Libero, Calabria Elisa, Piquer-Sirerol Salomé, Valle Giorgio, Perez-Tur Jordi, Michelucci Roberto, Nobile Carlo
Abstract excerpt
The leucine-rich, glioma inactivated 1 (LGI1)/Epitempin gene has been linked to two phenotypes as different as gliomagenesis and autosomal dominant lateral temporal epilepsy. Its function and the biochemical features of the encoded protein are unknown. We characterized the LGI1/Epitempin protein product by western blot analysis of mouse and human brain tissues. Two proteins of about 60 and 65 kDa were detected by...
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