Article
Genetics meets proteomics: perspectives for large population-based studies.
Nature reviews. Genetics - 1 Jan 2021
Suhre Karsten, McCarthy Mark I, Schwenk Jochen M
Abstract excerpt
Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the complex processes influencing human biology. Proteins represent intermediate phenotypes for disease and provide insight into how genetic and non-genetic risk factors are mechanistically linked to clinical outcomes. Associations between protein levels and DNA sequence variants that colocalize with risk alleles for common...
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