Article
N-Terminus Does Not Govern Protein Turnover of Schizosaccharomyces pombe CENP-A.
International journal of molecular sciences - 26 Aug 2020
Tan Hwei Ling, Zeng Yi Bing, Chen Ee Sin
Abstract excerpt
Centromere integrity underlies an essential framework for precise chromosome segregation and epigenetic inheritance. Although centromeric DNA sequences vary among different organisms, all eukaryotic centromeres comprise a centromere-specific histone H3 variant, centromeric protein A (CENP-A), on which other centromeric proteins assemble into the kinetochore complex. This complex connects chromosomes to mitotic...
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