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Fission Yeast CENP-C (Cnp3) Plays a Role in Restricting the Site of CENP-A Accumulation.

G3 (Bethesda, Md.) - 31 Jul 2018

Suma Michiko, Kitagawa Teppei, Nakase Yukiko, Nakazawa Norihiko, Yanagida Mitsuhiro, Matsumoto Tomohiro

Abstract excerpt

The centromere is a chromosomal locus where a microtubule attachment site, termed kinetochore, is assembled in mitosis. In most eukaryotes, with the exception of holocentric species, each chromosome contains a single distinct centromere. A chromosome with an additional centromere undergoes successive rounds of anaphase bridge formation and breakage, or triggers a cell cycle arrest imposed by DNA damage and...

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PMID: 29925533
DOI: 10.1534/g3.118.200486
PMCID: PMC6071599

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Fission Yeast CENP-C (Cnp3) Plays a Role in Restricting the Site of CENP-A Accumulation.PMID 29925533Read ↗

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