Article
Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus.
Immunity, inflammation and disease - 1 Dec 2020
Abdel-Gawad Abdelhady R, Shaheen Sameerah, Babteen Nouf A, Toraih Eman A, Elshazli Rami M, Fawzy Manal S, Gouda Nawal S
Abstract excerpt
OBJECTIVE: MicroRNAs are large family clusters of small noncoding RNAs that implicated in genetic and epigenetic regulation of several immunological processes and pathways. As an epigenetic modifier, the microRNA 17-92 cluster host gene (MIR17HG) has been shown to regulate the expression of genes involved in systemic lupus erythematosus (SLE) pathway. This study aimed to explore the association of MIR17HG...
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