Article
Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus.
Molecular biology reports - 1 Mar 2011
Zhang Junlong, Yang Bin, Ying Binwu, Li Dongdong, Shi Yunying, Song Xingbo, Cai Bei, Huang Zhuochun, Wu Yongkang, Wang Lanlan
Abstract excerpt
MicroRNAs (miRNAs) may play important roles in SLE, but genetic polymorphisms of miRNAs and their relationships with various autoantibodies present in SLE patients remain unclear. Here, we report that 213 SLE patients and 209 healthy individuals of Chinese had been taken into this case-control studies, which had been performed by selecting two miRNAs (hsa-mir-146a rs2910164 G>C, and hsa-mir-499 rs3746444 T>C) to...
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