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Article

MicroRNA-17-92a-1 Host Gene (MIR17HG) Expression Signature and rs4284505 Variant Association with Alopecia Areata: A Case-Control Study.

Genes - 12 Mar 2022

Faisal Salwa, Toraih Eman A, Atef Lina M, Hassan Ranya, Fouad Marwa M, Al Ageeli Essam, Fawzy Manal S, Abdalla Hussein Abdelaziz

Abstract excerpt

Accumulating evidence indicates the implication of microRNAs (miRs) in cutaneous and hair follicle immunobiology. We evaluated, for the first time, the miR-17-92a-1 cluster host gene (MIR17HG) expression in peripheral blood of 248 unrelated alopecia areata (AA) patients compared to 244 matched controls using Real-Time qPCR. We also tested its association with different rs4284505A>G genotypes (based on TaqMan...

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PMID: 35328059
DOI: 10.3390/genes13030505
PMCID: PMC8955921

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