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Article

Association between genetic variants of microRNA-21 and microRNA-155 and systemic lupus erythematosus: A case-control study from a Chinese population.

Journal of clinical laboratory analysis - 1 Jul 2022

Wang Rong, Wei Anji, Zhang Yingjie, Xu Guidan, Nong Xuejuan, Liu Chunhong, Zeng Yonglong, Huang Huatuo, Pang Xiaoxia, Wei Wujun, Wang Chunfang, Huang Huayi

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) is a common autoimmune disease, and its pathogenesis remains unclear. The alteration of genetic materials is believed to play a role in SLE development. This study evaluated the association between the genetic variants of microRNA-21 (miR-21) and microRNA-155 (miR-155) and SLE. METHODS: The SNaPshot genotyping method was used to detect the genotypes of selected SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35707883
DOI: 10.1002/jcla.24518
PMCID: PMC9279951

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