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Article

The role of IL-17 rs2275913, IL-17RC rs708567 and TGFB1 rs1800469 SNPs and IL-17A serum levels in patients with lupus nephritis.

Rheumatology international - 1 Dec 2021

Hristova Maria, Kamenarska Zornitsa, Dzhebir Gyulnas, Nikolova Svetla, Hristova Rozalia, Mihova Kalina, Vinkov Anton, Georgiev Tsvetoslav, Pozharashka Joana, Kaneva Radka, Savov Alexey, Koundurdjiev Atanas, Dourmishev Lyubomir

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease and polymorphisms in the cytokine genes and their receptors are thought to influence its development. The aim of this case-control study was to investigate the association of the IL-17A rs2275913, IL-17RC rs708567 and TGFB1 rs1800469 polymorphisms with SLE, its clinical manifestations and the polymorphisms influence on the IL-17A serum...

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Source

Identifiers

PMID: 34554306
DOI: 10.1007/s00296-021-04996-z

Genes

TGFB1
IL17A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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