Article
Association of the HLA-G gene +3142C>G polymorphism with systemic lupus erythematosus.
Tissue antigens - 1 Jun 2011
Consiglio C R, Veit T D, Monticielo O A, Mucenic T, Xavier R M, Brenol J C T, Chies J A B
Abstract excerpt
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease that affects several organs and systems. Its etiology remains unknown, although it is probably multifactorial. The human leukocyte antigen G (HLA-G) is a nonclassic major histocompatibility complex I molecule characterized by restricted expression and low DNA polymorphism. HLA-G plays a role in immunosuppression through different mechanisms....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.