Article
The impact of human single nucleotide polymorphisms on Bacillus Calmette-Guérin responses.
Vaccine - 11 Sept 2020
Messina Nicole L, Netea Mihai G, Curtis Nigel
Abstract excerpt
The influence of genetic variability on human immune responses has major implications for the understanding of disease mechanisms and host-pathogen interactions. Bacillus Calmette-Guérin (BCG) vaccine, which is given globally to protect against tuberculosis, has high variability in its protective efficacy against mycobacteria and its beneficial off-target (heterologous) effects. Single nucleotide polymorphisms...
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