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Genomic characteristics of two most widely used BCG vaccine strains: Danish 1331 and Pasteur 1173P2

21 Aug 2022

Abstract excerpt

BACKGROUND: Bacillus Calmette-Guérin (BCG) refers to a group of vaccine strains with unique genetic characteristics. BCG is the only available vaccine for preventing tuberculosis (TB). Genetic and biochemical variations among the BCG vaccine strains have been considered as one of the significant parameters affecting the variable protective efficacy of the vaccine against pulmonary tuberculosis. To track genetic...

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PMID: 35987561
DOI: 10.1186/s12864-022-08826-9

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