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Article

SMARCB1-deficient carcinomas of the head and neck region: a cytopathologic characterization.

Journal of the American Society of Cytopathology - 1 Jan 2000

Kezlarian Brie E, Lin Oscar, Dogan Snjezana

Abstract excerpt

INTRODUCTION: SMARCB1 encodes for a component of the SWI/SNF complex and is widely implicated in carcinogenesis. In the head and neck, SMARCB1-deficient carcinomas typically arise in the sinonasal tract but can be found at other sites. EZH2 inhibitors have emerged as potential targeted therapy against SWI/SNF-deficient tumors. We sought to characterize the cytomorphology of head and neck carcinomas with SMARCB1...

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Identifiers

PMID: 32839151
DOI: 10.1016/j.jasc.2020.07.134
PMCID: PMC7572880

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Source receipt: pubmed, retrieved 7 Sept 2026.

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