Article
The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer.
Oncogene - 29 Aug 2005
Mishra Lopa, Shetty Kirti, Tang Yi, Stuart August, Byers Stephen W
Abstract excerpt
The past three decades have seen an unremitting quest to identify and understand gastrointestinal stem cells, their plasticity in differentiating across cell types, as well as their role in normal, regenerative, and cancer cells. A fascinating hallmark of stem cells is their ability to undergo assymetric cell division, which entails replication of the DNA followed by division of the nucleus and partitioning of...
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