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Liver cancer: the role of stem cells

21 Nov 2005

Abstract excerpt

Studies of aggregation chimaeras and X-linked polymorphisms strongly suggest that liver tumours are derived from single cells (monoclonal), but the important question is, which cell? Stem cell biology and cancer are inextricably linked. In continually renewing tissues such as the gut mucosa and epidermis, where a steady flux of cells occurs from the stem cell zone to the terminally differentiated cells that are...

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PMID: 16300653
DOI: 10.1111/j.1365-2184.2005.00354.x

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