Article
Status of Gene Methylation and Polymorphism in Different Courses of Ulcerative Colitis and Their Comparison with Sporadic Colorectal Cancer.
Inflammatory bowel diseases - 15 Mar 2021
Liu Chen, Yuan Zi-Ying, Yuan Hao, Wu Ke-Xiang, Cao Bin, Ren Ke-Yu, Cui Ming-Juan, Liu Jun-Heng, Chen Hai-Xing, Pang Yao-Wei
Abstract excerpt
BACKGROUND: The objective of this study is to explore the common genetic and epigenetic mechanism of ulcerative colitis (UC) and sporadic colorectal cancer (SCRC) by observing genes methylation level and single nucleotide polymorphisms (SNPs) of different disease courses in UC and SCRC. METHODS: Two hundred subjects were enrolled, including 40 in the healthy control (HC) group, 50 in the short disease course UC...
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