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Article

Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer.

The American journal of gastroenterology - 1 Jul 2010

Garrity-Park Megan M, Loftus Edward V, Sandborn William J, Bryant Sandra C, Smyrk Thomas C

Abstract excerpt

OBJECTIVES: Patients with ulcerative colitis (UC) are at increased risk for developing colorectal cancer (CRC). Surveillance in this at-risk population remains challenging. We assessed the methylation status of genes in the non-neoplastic mucosa of UC-CRC patients and controls to identify potential biomarkers of CRC. METHODS: We evaluated the methylation status of 10 genes (p16, p14, runt-related transcript...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20160714
DOI: 10.1038/ajg.2010.22

Genes

RUNX3

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