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Article

Efficient and effective control of confounding in eQTL mapping studies through joint differential expression and Mendelian randomization analyses.

Bioinformatics (Oxford, England) - 20 Apr 2021

Fan Yue, Zhu Huanhuan, Song Yanyi, Peng Qinke, Zhou Xiang

Abstract excerpt

MOTIVATION: Identifying cis-acting genetic variants associated with gene expression levels-an analysis commonly referred to as expression quantitative trait loci (eQTLs) mapping-is an important first step toward understanding the genetic determinant of gene expression variation. Successful eQTL mapping requires effective control of confounding factors. A common method for confounding effects control in eQTL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32790868
DOI: 10.1093/bioinformatics/btaa715
PMCID: PMC8058772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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