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Article

Evaluation of the role of B7-H3 haplotype in association with impaired B7-H3 expression and protection against type 1 diabetes in Chinese Han population.

BMC endocrine disorders - 12 Aug 2020

Ding Sisi, Shan Yimei, Sun Lili, Li Sicheng, Jiang Rong, Chang Xin, Huang Ziyi, Sun Jing, Liu Cuiping, Fang Chen, Zhang Xueguang

Abstract excerpt

BACKGROUND: Type 1 Diabetes (T1D) is a T cell-mediated autoimmune disorder caused by the destruction of insulin-secreting cells. B7-H3 (CD276) plays a vital role in T cell response. However, B7-H3 expression and its clinical significance in T1D remain unclear. The aim of this study was to investigate the correlations between the expression of B7-H3 and clinical parameters in T1D patients. The possible role of...

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Identifiers

PMID: 32787907
DOI: 10.1186/s12902-020-00592-7
PMCID: PMC7425597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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