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Article

Association analysis of B7-H3 and B7-H4 gene single nucleotide polymorphisms in susceptibility to ankylosing spondylitis in eastern Chinese Han population.

International journal of immunogenetics - 1 Dec 2021

Chen Yuting, Yang Hui, Xu Shanshan, Shen Jiran, Xu Wei, Shao Ming, Pan Faming

Abstract excerpt

This study was conducted to describe the association between the genetic variation of the recently identified immune checkpoint molecules B7-H3 and B7-H4, and the susceptibility to ankylosing spondylitis (AS). Two single nucleotide polymorphisms (SNPs) of B7-H3 gene and three SNPs of B7-H4 gene were genotyped in 649 AS patients and 646 age- and sex-matched healthy controls. Allele, genotype frequencies and...

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PMID: 34555253
DOI: 10.1111/iji.12559

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