Article
The characteristic expression of B7-H3 and B7-H4 in liver biopsies from patients with HBV-related acute-on-chronic liver failure.
Pathology international - 1 Oct 2012
Guo Guoning, Cao Dayan, Xu Huan, Ruan Zhihua, Fei Lei, Xie Zhunyi, Wu Yuzhang, Chen Yongwen
Abstract excerpt
Hepatitis B virus (HBV) is a major public health problem, and HBV-related acute-on-chronic liver failure (HBV-ACLF) has an extremely poor prognosis due to a lack of effective treatments. B7-H3 and B7-H4 are two novel members of the B7 superfamily that are actively involved in regulating the pathogenesis of infectious diseases. However, the intrahepatic expression of both members in HBV-ACLF patients has yet to be...
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