Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Reduced mitochondrial DNA copy number is associated with the haplogroup, and some clinical features of breast cancer in Mexican patients.

Gene - 30 Nov 2020

Domínguez-de-la-Cruz Eduardo, Muñoz María de Lourdes, Pérez-Muñoz Ashael, García-Hernández Normand, Moctezuma-Meza Christian, Hinojosa-Cruz Juan Carlos

Abstract excerpt

Mitochondrial DNA (mtDNA) copy number and mitochondrial DNA haplogroups have been associated with different types of cancer, including breast cancer, because they alter cellular energy metabolism. However, whether mtDNA copy number or haplogroups are predictors of oxidative stress-related risks in human breast cancer tissue in Mexican patients remains to be determined. Using quantitative real-time PCR assays and...

Topics

Adult
Breast Neoplasms
Case-Control Studies
DNA Copy Number Variations
DNA, Mitochondrial
Female
Genetic Predisposition to Disease
Haplotypes
Humans
Mexico

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mitochondria

Source

Identifiers

PMID: 32783993
DOI: 10.1016/j.gene.2020.145047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced mitochondrial DNA copy number is associated with the haplogroup, and some clinical features of breast cancer in Mexican patients.PMID 32783993Read ↗

Potential Association of Mitochondrial Haplogroups and A8860G Mutation with Breast Cancer RiskSemantic proximity Read ↗

Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patientsSemantic proximity Read ↗

Correlational study on mitochondrial DNA mutations as potential risk factors in breast cancer.Semantic proximity Read ↗

An A10398G mitochondrial DNA alteration is related to increased risk of breast cancer, and associates with Her2 positive receptor.Semantic proximity Read ↗

Mitochondrial DNA alterations correlate with the pathological status and the immunological ER, PR, HER-2/neu, p53 and Ki-67 expression in breast invasive ductal carcinoma.Semantic proximity Read ↗

Unraveling the genetic connections for mitochondrial DNA control region and breast cancer susceptibility.Semantic proximity Read ↗

Mitochondrial Control Region Variants Related to Breast CancerSemantic proximity Read ↗

Current understanding of mitochondrial DNA in breast cancer.Semantic proximity Read ↗

Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancerSemantic proximity Read ↗

Mitochondrial DNA Content as a Potential Marker to Predict Response to Anthracycline in Breast Cancer PatientsSemantic proximity Read ↗

Mitochondrial DNA Copy Number in Peripheral Blood Cells and Risk of Developing Breast Cancer.Semantic proximity Read ↗

Mitochondrial genotype and breast cancer predisposition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.