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Article

Detecting Allele-Specific Alternative Splicing from Population-Scale RNA-Seq Data.

American journal of human genetics - 3 Sept 2020

Demirdjian Levon, Xu Yungang, Bahrami-Samani Emad, Pan Yang, Stein Shayna, Xie Zhijie, Park Eddie, Wu Ying Nian, Xing Yi

Abstract excerpt

RNA sequencing (RNA-seq) is a powerful technology for studying human transcriptome variation. We introduce PAIRADISE (Paired Replicate Analysis of Allelic Differential Splicing Events), a method for detecting allele-specific alternative splicing (ASAS) from RNA-seq data. Unlike conventional approaches that detect ASAS events one sample at a time, PAIRADISE aggregates ASAS signals across multiple individuals in a...

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Identifiers

PMID: 32781045
DOI: 10.1016/j.ajhg.2020.07.005
PMCID: PMC7477012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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