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Article

DirectASRM: uncovering allele-specific post-transcriptional RNA modifications through direct RNA sequencing.

Bioinformatics (Oxford, England) - 2 Jul 2026

Dai Jiayin, Zhang Yuxin, Li Jiayi, Ma Jiongming, Chen Kunqi, Meng Jia, Rigden Daniel J, Wei Zhen, Lin Shaofeng, Xu Qingru

Abstract excerpt

SUMMARY: We developed DirectASRM, a comprehensive database for the systematic identification, integration, and annotation of allele-specific RNA modifications (ASRMs) from direct RNA sequencing data. DirectASRM enables single-base, transcript-level detection of ASRMs across multiple RNA modification types, diverse organisms and condition-specific contexts. The database further evaluates the confidence of each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42330361
DOI: 10.1093/bioinformatics/btag432
PMCID: PMC13350993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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