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Article

Immunosuppressive role of CD11b+ CD33+ HLA-DR- myeloid-derived suppressor cells-like blast subpopulation in acute myeloid leukemia.

Cancer medicine - 1 Oct 2020

Hyun Shin Young, Na Eun Jung, Jang Ji Eun, Chung Haerim, Kim Soo Jeong, Kim Jin Seok, Kong Jee Hyun, Shim Kwang Yong, Lee Jong In, Min Yoo Hong, Cheong June-Won

Abstract excerpt

OBJECTIVE: Myeloid-derived suppressor cells (MDSCs) facilitate tumor growth and development by suppressing T cell function; however, their role in acute myeloid leukemia (AML) remains unclear. Here, we investigated the immunosuppressive role and prognostic value of blasts with an MDSC-like phenotype. METHODS: CD11b+ CD33+ HLA-DR- MDSC-like blasts from bone marrow mononuclear cells of patients with AML were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32780544
DOI: 10.1002/cam4.3360
PMCID: PMC7541151

Genes

CD33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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