Article
Circulating Monocytic Myeloid‐Derived Suppressor Cells Are Elevated and Associated with Poor Prognosis in Acute Myeloid Leukemia
1 Jan 2020
Abstract excerpt
Background . Monocytic myeloid‐derived suppressor cells (M‐MDSCs) characterized with the phenotype of CD14 + HLA‐DR low/- have attracted a lot of attention in the field of human tumor immunology. However, little is known about the roles of M‐MDSCs in acute myeloid leukemia (AML) as opposed to their multiple roles in solid tumors. Methods . We examined the frequencies of M‐MDSCs identified for CD14 + HLA‐DR low/-...
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