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Prognostic value of myeloid-derived suppressor-like cells in acute myeloid leukemia: insights from immunophenotyping and clinical correlations.

Immunologic research - 14 Dec 2024

Sant'Ana Alexia N, Dias Camila K, Nunes Vitória B S, Farias Mariela G, Alegretti Ana P, Portela Pâmela, Calvache Ebellins T, Meirelles Maria F, Daudt Liane E, Michalowski Mariana B, Paz Alessandra A, Figueiró Fabrício

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population that acts on both innate and adaptive immunity, fostering immune escape in tumors and contributing to cancer progression. Despite the lack of definitive markers for immunophenotyping MDSCs, particularly the polymorphonuclear (PMN-MDSC) subset, these cells seem to play a crucial role in acute myeloid leukemia (AML) patients' prognosis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39673675
DOI: 10.1007/s12026-024-09558-6

Genes

CD36
FLT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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