Article
Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.
BioMed research international - 1 Jan 2020
Gutiérrez-Castañeda Luz D, Gamboa Mauricio, Nova John A, Pulido Leonardo, Tovar-Parra Jose D
Abstract excerpt
INTRODUCTION: Mutations in the BRAF, NRAS, and C-KIT genes have been associated with the histopathological characteristics of melanoma. Likewise, the incidence of each of these subtypes changes according to the geographical origin of the population analyzed. OBJECTIVE: To determine the mutation frequency in exons 11 and 15 of the BRAF gene, exons 1 and 2 of the NRAS gene, and exons 11, 13, and 17 of the C-KIT...
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