Article

BRAF, C-KIT, and NRAS mutations correlated with different clinicopathological features: an analysis of 691 melanoma patients from a single center

2021-02-09

Abstract excerpt

<h4>Aims: </h4> To analyze the prevalence and relevance of pathogenetic mutations in BRAF, C-KIT, and NRAS in Chinese melanoma patients to provide some potential reference for the targeted treatment in China. Methods We described the frequency and distribution of BRAF, NRAS, and C-KIT mutation in 691 melanoma patients, and analyze the statistical significance of different gene mutation with clinicopathological f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e59cab0f-2322-539c-9304-17f8cb0d878f
DOI: 10.21203/rs.3.rs-202208/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

BRAF, C-KIT, and NRAS mutations correlated with different clinicopathological features: an analysis of 691 melanoma patients from a single centerDOI 10.21203/rs.3.rs-202208/v1Read

Gene Mutation Characteristics and Clinical Prognosis of Head and Neck Mucosal MelanomaSemantic proximity Read

Frequency of mutations in BRAF, NRAS, and KIT in different populations and histological subtypes of melanoma: a systemic reviewSemantic proximity Read

Clinical characteristics associated with BRAF, NRAS and KIT mutations in Japanese melanoma patientsSemantic proximity Read

Effects of BRAF V600E and NRAS mutational status on the progression‑free survival and clinicopathological characteristics of patients with melanomaSemantic proximity Read

Clinicopathological characteristics and mutation profiling in primary cutaneous melanoma.Semantic proximity Read

Gene mutations and clinical prognosis of mucosal melanoma in different locations of head and neck.Semantic proximity Read

Prevalence of BRAF V600E mutation in Chinese melanoma patients: Large scale analysis of BRAF and NRAS mutations in a 432-case cohortSemantic proximity Read

BRAF, NRAS and C-KIT Advanced Melanoma: Clinico-pathological Features, Targeted-Therapy Strategies and Survival.Semantic proximity Read

Prevalence of BRAF and NRAS mutations in cutaneous melanoma patients in Taiwan.Semantic proximity Read

Low incidence of BRAF and NRAS mutations in a population with a high incidence of melanoma.Semantic proximity Read

NRAS mutations in primary and metastatic melanomas of Japanese patients.Semantic proximity Read

Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma.Semantic proximity Read