BRAF and NRAS Mutations and the Association with Prognosis of Acral Lentiginous and Nodular Melanomas in Indonesia.

doi:10.31557/APJCP.2024.25.10.3525

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Article

BRAF and NRAS Mutations and the Association with Prognosis of Acral Lentiginous and Nodular Melanomas in Indonesia.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2024

Anwar Sumadi Lukman, Ferronika Paranita, Cahyono Roby, Sugandhi William, Pradana Gizza Dandy

Abstract excerpt

BACKGROUND: Melanomas are rare yet the most aggressive skin cancer among Asians. Clinical presentation, risk factors, and the underlying molecular mechanisms are strikingly different from cutaneous melanoma in Caucasians. METHODS: Mutation patterns of BRAF and NRAS genes were examined from DNAs derived from primary melanoma tumor tissues (fresh tissues or formalin-fixed paraffin-embedded samples) using...

Topics

Humans
Proto-Oncogene Proteins B-raf
Melanoma
GTP Phosphohydrolases
Female
Male
Membrane Proteins
Prognosis
Middle Aged
Skin Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Indonesia

Adult

Follow-Up Studies

Aged

Biomarkers, Tumor

Melanoma, Cutaneous Malignant

Survival Rate

Source

Open in PubMed

Identifiers

PMID: 39471018
DOI: 10.31557/APJCP.2024.25.10.3525

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