Article
BRAF and NRAS Mutations and the Association with Prognosis of Acral Lentiginous and Nodular Melanomas in Indonesia.
Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2024
Anwar Sumadi Lukman, Ferronika Paranita, Cahyono Roby, Sugandhi William, Pradana Gizza Dandy
Abstract excerpt
BACKGROUND: Melanomas are rare yet the most aggressive skin cancer among Asians. Clinical presentation, risk factors, and the underlying molecular mechanisms are strikingly different from cutaneous melanoma in Caucasians. METHODS: Mutation patterns of BRAF and NRAS genes were examined from DNAs derived from primary melanoma tumor tissues (fresh tissues or formalin-fixed paraffin-embedded samples) using...
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