Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational Profile of Driver Genes in Brazilian Melanomas.

Journal of global oncology - 1 Nov 2019

Vicente Anna Luiza S A, Crovador Camila S, Macedo Graziela, Scapulatempo-Neto Cristovam, Reis Rui M, Vazquez Vinicius L

Abstract excerpt

PURPOSE: Mutation testing of the key genes involved in melanoma oncogenesis is now mandatory for the application of targeted therapeutics. However, knowledge of the mutational profile of melanoma remains largely unknown in Brazil. PATIENTS AND METHODS: In this study, we assessed the mutation status of melanoma driver genes BRAF, NRAS, TERT, KIT, and PDGFRA in a cohort of 459 patients attended at Barretos Cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Melanoma
Share to GTP Phosphohydrolases
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Skin Neoplasms

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 31756131
DOI: 10.1200/JGO.19.00169
PMCID: PMC6882511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational Profile of Driver Genes in Brazilian Melanomas.PMID 31756131Read ↗

Genetic diversity in melanomagenesis: a comprehensive analysis of BRAF, NRAS, KIT and novel mutations across melanoma subtypes.Semantic proximity Read ↗

Frequency of mutations in BRAF, NRAS, and KIT in different populations and histological subtypes of melanoma: a systemic reviewSemantic proximity Read ↗

Clinicopathological characteristics and mutation profiling in primary cutaneous melanoma.Semantic proximity Read ↗

[ Spectrum of oncogene mutations is different in melanoma subtypes].Semantic proximity Read ↗

Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.Semantic proximity Read ↗

MAPK Pathway and TERT Promoter Gene Mutation Pattern and Its Prognostic Value in Melanoma Patients: A Retrospective Study of 2,793 Cases.Semantic proximity Read ↗

Low incidence of BRAF and NRAS mutations in a population with a high incidence of melanoma.Semantic proximity Read ↗

The molecular profile of metastatic melanoma in Australia.Semantic proximity Read ↗

Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma.Semantic proximity Read ↗

BRAF, C-KIT, and NRAS mutations correlated with different clinicopathological features: an analysis of 691 melanoma patients from a single centerSemantic proximity Read ↗

Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing.Semantic proximity Read ↗

BRAF V600E Mutation in Malignant Melanoma-A Romanian Research Experience.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.