Article
Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.
Journal of clinical laboratory analysis - 1 Dec 2020
Fawzy Manal S, Abu AlSel Baraah T, Toraih Eman A
Abstract excerpt
BACKGROUND: MicroRNA (miRNA) processing machinery gene variant was associated with several diseases. We aimed to explore for the first time the association of machinery gene (DROSHA rs10719A/G; DICER1 rs3742330A/G; RAN rs14035C/T; and XPO5 rs11077T/G) variants with the susceptibility and phenotype of end-stage renal disease (ESRD). METHOD: A total of 281 participants (98 ESRD patients and 183 healthy volunteers)...
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