Article
Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma.
PloS one - 1 Jan 2016
Kim Mi Na, Kim Jung Oh, Lee Seung Min, Park Hana, Lee Ju Ho, Rim Kyu Sung, Hwang Seong Gyu, Kim Nam Keun
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in microRNA machinery genes might affect microRNA processing and subsequently impact tumorigenesis. The aim of this study was to investigate the associations between SNPs in microRNA machinery genes and hepatocellular carcinoma (HCC) in a Korean population. Genotyping of six SNPs in microRNA machinery genes was performed using blood samples from 147 patients with HCC and 209...
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