Article
Association of polymorphisms in microRNA machinery genes (DROSHA, DICER1, RAN, and XPO5) with risk of idiopathic primary ovarian insufficiency in Korean women.
Menopause (New York, N.Y.) - 1 Oct 2013
Rah HyungChul, Jeon Young Joo, Lee Bo Eun, Kim Jung O, Shim Sung Han, Lee Woo Sik, Choi Dong Hee, Kim Ji Hyang, Kim Nam Keun
Abstract excerpt
OBJECTIVE: The aim of our study was to investigate whether polymorphisms in microRNA machinery genes are associated with the risk of primary ovarian insufficiency (POI). METHODS: We genotyped 136 POI patients and 236 controls among Korean women for nine single nucleotide polymorphisms (SNPs; DROSHA rs6877842 and rs10719; DICER1 rs13078 and rs3742330; RAN rs14035; and XPO5 , , , and...
