Article
Single nucleotide polymorphisms of microRNA processing machinery genes and outcome of hepatocellular carcinoma.
PloS one - 1 Jan 2014
Liu Shuang, An Jie, Lin Jianhong, Liu Yanli, Bao Lidao, Zhang Wen, Zhao Jian-Jun
Abstract excerpt
MicroRNA (miRNA)-related single nucleotide polymorphisms (miR-SNPs) can affect cancer development, treatment efficacy and patients prognosis. We examined 6 miR-SNPs in miRNA processing machinery genes including exportin 5 (XPO5) (rs11077), Ran-GTPase (RAN) (rs14035), Dicer (rs3742330), Trinucleotide Repeat Containing 6B (TNRC6B) (rs9623117), GEMIN3 (rs197412), GEMIN4 () in 108 surgically resected HCC...
