Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.

PloS one - 1 Jan 2015

Cho Sung Hwan, Ko Jung Jae, Kim Jung Oh, Jeon Young Joo, Yoo Jung Ki, Oh Jisu, Oh Doyeun, Kim Jong Woo, Kim Nam Keun

Abstract excerpt

MicroRNAs play an important role in cancer initiation and development. The aim of this study was to investigate whether polymorphisms in miRNA machinery genes are associated with the development of colorectal cancer (CRC). RAN rs14035 CT heterozygotes and T allele carriers (CT + TT) genotypes had lower risk of CRC, while the DICER1 rs3742330, DROSHA rs10719, and XPO5 rs11077 polymorphisms were not associated with...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD-box RNA Helicases
Share to Folic Acid
Share to Homocysteine
Share to Karyopherins
Share to ran GTP-Binding Protein
Share to Ribonuclease III
Share to RNA, Neoplasm
Share to Tumor Burden

Source

Open in PubMed Open full text

Identifiers

PMID: 26147304
DOI: 10.1371/journal.pone.0131125
PMCID: PMC4492935

Genes

RAN
XPO5
DICER1
DROSHA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.PMID 26147304Read ↗

Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma.Semantic proximity Read ↗

miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinomaSemantic proximity Read ↗

Genetic variants in miRNA machinery genes associated with clinicopathological characteristics and outcomes of gastric cancer patients.Semantic proximity Read ↗

Association between genetic variants in DICER1 and cancer risk: An updated meta-analysis.Semantic proximity Read ↗

Evaluation of genetic variants in microRNA biosynthesis genes and risk of breast cancer in Chinese women.Semantic proximity Read ↗

Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.Semantic proximity Read ↗

Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.Semantic proximity Read ↗

Association between the DICER rs1057035 polymorphism and cancer risk: evidence from a meta-analysis of 1,2675 individuals.Semantic proximity Read ↗

Association of miRNA biosynthesis genes DROSHA and DGCR8 polymorphisms with cancer susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms of microRNA processing machinery genes and outcome of hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variation in DROSHA 3'UTR regulated by hsa-miR-27b is associated with bladder cancer risk.Semantic proximity Read ↗

Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.