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Hepatic Fat-Genetic Risk Score Predicts Hepatocellular Carcinoma in Patients With Cirrhotic HCV Treated With DAAs.

Hepatology (Baltimore, Md.) - 1 Dec 2020

Degasperi Elisabetta, Galmozzi Enrico, Pelusi Serena, D'Ambrosio Roberta, Soffredini Roberta, Borghi Marta, Perbellini Riccardo, Facchetti Floriana, Iavarone Massimo, Sangiovanni Angelo, Valenti Luca, Lampertico Pietro

Abstract excerpt

BACKGROUND AND AIMS: Genetic factors and steatosis predispose to hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus; however, their impact in patients with cirrhosis cured by direct-acting antivirals (DAAs) is still undefined. We assessed the association between a genetic risk score (GRS) of hepatic fat accumulation, combining variants in PNPLA3 (patatin-like phospholipase domain containing...

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PMID: 32762045
DOI: 10.1002/hep.31500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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