Article

Genome-wide association and gene-virus interaction study of liver disease in hepatitis C virus-infected patients

2025-10-17

Abstract excerpt

<h4>Background and Aims</h4> Chronic hepatitis C (CHC) can progress to cirrhosis and hepatocellular carcinoma (HCC). This study aimed to identify genetic determinants and host-viral interactions that drive this progression to inform risk stratification and personalised treatment strategies. <h4>Methods</h4> We performed a genome-wide association study (GWAS) of cirrhosis (2,829 cases and 1,515 CHC controls), fol...

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Literature Corpus work: 4673ac53-ef28-5362-9564-83c196be5655
DOI: 10.1101/2025.10.12.25337816

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