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Article

High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.

PloS one - 20 Dec 2010

Poonia Bhawna, Kijak Gustavo H, Pauza C David

Abstract excerpt

BACKGROUND: We investigated the genetics of Fc receptors, which function as activating receptors on immune cells and help to control HIV through antibody-mediated cellular cytotoxicity. Thus, Fc receptors may be important for virus immunity but might also promote immune hyperactivation that would enhance infection. METHODOLOGY/PRINCIPAL FINDINGS: We measured abundance of low and high activity alleles in two Fc...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21187939
DOI: 10.1371/journal.pone.0015562
PMCID: PMC3004964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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