Article
Participation of Zip3, a ZIP domain-containing protein, in stress response and virulence in Cryptococcus gattii.
Fungal genetics and biology : FG & B - 1 Nov 2020
Garcia Ane Wichine Acosta, Kinskovski Uriel Perin, Diehl Camila, Reuwsaat Júlia Catarina Vieira, Motta de Souza Heryk, Pinto Helber Barboza, Trentin Danielle da Silva, de Oliveira Haroldo Cesar, Rodrigues Marcio L, Becker Emilene Mendes, Kmetzsch Livia, Vainstein Marilene Henning, Staats Charley Christian
Abstract excerpt
Cryptococcus gattii is an etiologic agent of cryptococcosis, a potentially fatal disease that affects humans and animals. The successful infection of mammalian hosts by cryptococcal cells relies on their ability to infect and survive in macrophages. Such phagocytic cells present a hostile environment to intracellular pathogens via the production of reactive nitrogen and oxygen species, as well as low pH and...
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