Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zinc Cluster Transcription Factors Alter Virulence in Candida albicans

9 Dec 2016

Abstract excerpt

Almost all humans are colonized with Candida albicans However, in immunocompromised individuals, this benign commensal organism becomes a serious, life-threatening pathogen. Here, we describe and analyze the regulatory networks that modulate innate responses in the host niches. We identified Zcf15 and Zcf29, two Zinc Cluster transcription Factors (ZCF) that are required for C. albicans virulence. Previous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Immunodeficiency and Autoimmune Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27932543
DOI: 10.1534/genetics.116.195024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zinc Cluster Transcription Factors Alter Virulence in Candida albicansPMID 27932543Read ↗

An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis.Semantic proximity Read ↗

Strain variation in the Candida albicans iron limitation response.Semantic proximity Read ↗

Activation and alliance of regulatory pathways in C. albicans during mammalian infection.Semantic proximity Read ↗

Phenotypic analysis of a family of transcriptional regulators, the zinc cluster proteins, in the human fungal pathogen Candida glabrata.Semantic proximity Read ↗

Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulenceSemantic proximity Read ↗

<i>Candida albicans</i> oropharyngeal infection is an exception to iron-based nutritional immunitySemantic proximity Read ↗

Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism.Semantic proximity Read ↗

<i>Candida glabrata</i> maintains two Hap1 homologs, Zcf27 and Zcf4, for distinct roles in ergosterol gene regulation to mediate sterol homeostasis under azole and hypoxic conditionsSemantic proximity Read ↗

Post-transcriptional regulation of the Sef1 transcription factor controls the virulence of Candida albicans in its mammalian host.Semantic proximity Read ↗

In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.Semantic proximity Read ↗

Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicansSemantic proximity Read ↗

Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory CircuitSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.