Article
Quantitative evaluation of the role of the microenvironment in the phenotype, metabolism, and drug resistance of PDAC tumor organoids
2025-01-02
Abstract excerpt
Tumor organoids are powerful tools to study cancer. However, the clinical translation of organoid-based studies depends on how closely the organoid scaffolding material recapitulates the tumor extracellular matrix (ECM). We present a quantitative analysis of the effect of scaffold composition on the phenotype, tissue remodeling, metabolism, and drug resistance of pancreatic ductal adenocarcinoma (PDAC) organoids....
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Identifiers and source
- Literature Corpus work
- 39719854-31fe-5399-83be-c1b2f03c14cd
- DOI
- 10.1101/2024.12.31.630904