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Genome-wide DNA methylation profiling identifies epigenetic signatures of gastric cardiac intestinal metaplasia

31 Jul 2020

Abstract excerpt

Abstract Background Measuring the DNA methylome may offer the opportunity to identify novel disease biomarkers and insights into disease mechanisms. Although aberrant DNA methylation has been investigated in many human cancers and precancerous lesions, the DNA methylation landscape of gastric cardiac intestinal metaplasia (IM) remains unknown. Therefore, we aimed to investigate the genome-wide DNA methylation...

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PMID: 32736574
DOI: 10.1186/s12967-020-02453-2

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