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Analysis of the clinical significance of DNA methylation in gastric cancer based on a genome-wide high-resolution array

1 Nov 2019

Abstract excerpt

BACKGROUND: Aberrant DNA methylation is involved in gastric carcinogenesis and may serve as a useful biomarker in the diagnosis and detection of gastric cancer (GC) recurrence. RESULTS: A total of 157 patients who received surgery for GC were enrolled in the present study. A genome-wide methylation analysis was performed in tumor and adjacent normal tissues for the discovery set of 16 GC patients; the top three...

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PMID: 31675985
DOI: 10.1186/s13148-019-0747-5

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