Article
Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).
Cancer letters - 1 Dec 2011
Balassiano Karen, Lima Sheila, Jenab Mazda, Overvad Kim, Tjonneland Anne, Boutron-Ruault Marie Christine, Clavel-Chapelon Françoise, Canzian Federico, Kaaks Rudolf, Boeing Heiner, Meidtner Karina, Trichopoulou Antonia, Laglou Pagona, Vineis Paolo, Panico Salvatore, Palli Domenico, Grioni Sara, Tumino Rosario, Lund Eiliv, Bueno-de-Mesquita H Bas, Numans Mattjis E, Peeters Petra H M, Ramon Quirós J, Sánchez María-José, Navarro Carmen, Ardanaz Eva, Dorronsoro Miren, Hallmans Göran, Stenling Roger, Ehrnström Roy, Regner Sara, Allen Naomi E, Travis Ruth C, Khaw Kay-Tee, Offerhaus G Johan A, Sala Nuria, Riboli Elio, Hainaut Pierre, Scoazec Jean-Yves, Sylla Bakary S, Gonzalez Carlos A, Herceg Zdenko
Abstract excerpt
Epigenetic events have emerged as key mechanisms in the regulation of critical biological processes and in the development of a wide variety of human malignancies, including gastric cancer (GC), however precise gene targets of aberrant DNA methylation in GC remain largely unknown. Here, we have combined pyrosequencing-based quantitative analysis of DNA methylation in 98 GC cases and 64 controls nested within the...
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