Article
Matrix Metalloproteinase-1 Genotype Contributes to the Risk of Non-solid Tumor in Childhood Leukemia.
Anticancer research - 1 Oct 2016
Pei Jen-Sheng, Hsu Pei-Chen, Chou An-Kuo, Tsai Chia-Wen, Chang Wen-Shin, Hsiao Chieh-Lun, Hsu Yuan-Nian, Cheng Shun-Ping, Bau DA-Tian
Abstract excerpt
AIM: Up-regulation of metalloproteinase (MMPs) proteins have been shown in various types of solid cancers and the genotype of MMP1 has been associated with the risk of solid cancers. However, the contribution of MMP1 genotype to leukemia has never been investigated to our knowledge. Therefore, in this study we aimed to evaluate the contribution of the genotypic variants in the promoter region of MMP1 to childhood...
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