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Article

RNA helicase p68 inhibits the transcription and post-transcription of Pkd1 in ADPKD.

Theranostics - 1 Jan 2020

Zhang Lu, Li Linda Xiaoyan, Zhou Julie Xia, Harris Peter C, Calvet James P, Li Xiaogang

Abstract excerpt

Background: Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of the PKD1 and PKD2 genes. Dysregulation of the expression of PKD genes, the abnormal activation of PKD associated signaling pathways, and the expression and maturation of miRNAs regulates cyst progression. However, the upstream factors regulating these abnormal processes in ADPKD remain elusive. Methods: To investigate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32724471
DOI: 10.7150/thno.47315
PMCID: PMC7381742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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