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Article

Src Family Tyrosine Kinases in Intestinal Homeostasis, Regeneration and Tumorigenesis

23 Jul 2020

Abstract excerpt

Src, originally identified as an oncogene, is a membrane-anchored tyrosine kinase and the Src family kinase (SFK) prototype. SFKs regulate the signalling induced by a wide range of cell surface receptors leading to epithelial cell growth and adhesion. In the intestine, the SFK members Src, Fyn and Yes regulate epithelial cell proliferation and migration during tissue regeneration and transformation, thus...

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PMID: 32717909
DOI: 10.3390/cancers12082014

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