Article
Src activity is increased in gastrointestinal stromal tumors--analysis of associations with clinical and other molecular tumor characteristics.
Journal of surgical oncology - 1 May 2014
Rotert Julia Valerie, Leupold Jörg, Hohenberger Peter, Nowak Kai, Allgayer Heike
Abstract excerpt
BACKGROUND: Increased activity of Src has been found in several human cancers, and often is associated with poor clinical outcome. The present study aimed to determine whether Src activity is increased in gastrointestinal stromal tumors (GIST), and whether it correlates with established tumor or patient characteristics and prognosis. METHODS: Tumor/normal tissues of 29 patients were analyzed for Src...
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